Radian B Muscle Rub 100g

Product Information

The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss. Frequency not known: Acute generalised exanthematous pustulosis (AGEP), photosensitivity reactions. Radian B Pain Relief Spray is used to provide relief from muscular and rheumatic aches and pains. This includes: In children ingestion of more than 400mg/kg may cause symptoms. In adults the dose response effect is less clear cut. The half-life in overdose is 1.5-3 hours.

Radian B - Health | Pharmacy and Prescriptions - Boots Radian B - Health | Pharmacy and Prescriptions - Boots

Radian B has multiple actions in different inflammatory pathways involved in acute and chronic inflammation. The main effects reported in ibuprofen are related to the control of pain, fever and acute inflammation by the inhibition of the synthesis of prostanoids by COX-1 and COX-2. Pain relief is attributed to peripheral affected regions and central nervous system effects in the pain transmission mediated by the dorsal horn and higher spinothalamic tract. Some reports have tried to link the pain regulation with a possible enhancement on the synthesis of endogenous cannabinoids and action on the NMDA receptors. The effect on pain has been shown to be related to the cortically evoked potentials. Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis have been reported rarely in association with the use of NSAIDs (see section 4.8). Patients appear to be at highest risk of these reactions early in the course of therapy, the onset of the reaction occurring in the majority of cases within the first month of treatment. Acute generalised exanthematous pustulosis (AGEP) has been reported in relation to ibuprofen-containing products. Ibuprofen should be discontinued, at the first appearance of signs and symptoms of severe skin reactions, such as skin rash, mucosal lesions, or any other sign of hypersensitivity.Haemodialysis is the treatment of choice for severe poisoning and should be considered in patients with plasma salicylate concentrations >700mg/L (5.1mmol/L), or lower concentrations associated with severe clinical or metabolic features. Patients under ten years or over 70 have increased risk of salicylate toxicity and may require dialysis at an earlier stage. Oral NSAIDs, including ibuprofen, can sometimes be associated with renal impairment, aggravation of active peptic ulcers, and can induce allergic bronchial reactions in susceptible asthmatic patients. Although the systemic absorption of topically applied ibuprofen is less than for oral dosage forms, these complications can occur in rare cases. For these reasons, patients with a history of kidney problems, an active peptic ulcer, asthma or intolerance to aspirin or ibuprofen should seek medical advice before using Radian B Ibuprofen 5% w/w Gel.

Thornton and Ross Products | Thornton and Ross

Uncommon features include haematemesis, hyperpyrexia, hypoglycaemia, hypokalaemia, thrombocytopaenia, increased INR/PTR, intravascular coagulation, renal failure and non-cardiac pulmonary oedema. Adults and adolescents over 14 years should squeeze 5 to 10cm of the gel from the tube and rub this gently into the affected area until the gel is absorbed.Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs. Radian B Hypertension interaction Digestive problems such as abdominal pain or indigestion, particularly in people with a history of stomach ulcers. Radian B is rapidly metabolized and eliminated in the urine thus, this via accounts for more than 90% of the administered dose. It is completely eliminated in 24 hours after the last dose and almost all the administered dose goes through metabolism, representing about 99% of the eliminated dose. The biliary excretion of unchanged drug and active phase II metabolites represents 1% of the administered dose.

Radian B Muscle Rub - Patient Information Leaflet (PIL) - (emc) Radian B Muscle Rub - Patient Information Leaflet (PIL) - (emc)

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Wash your hands thoroughly after applying the lotion to avoid getting it in your eyes or transferring it to sensitive areas of skin. The manufacturer of this medicine recommends that mothers should avoid using this medicine while breastfeeding. However, ibuprofen taken by mouth passes into breast milk in such small quantities that it is unlikely to harm the baby, hence ibuprofen gel is also unlikely to be harmful. As with all medicines, seek medical advice from your doctor before using this medicine if you are breastfeeding. Central nervous system features including confusion, disorientation, coma and convulsions are less common in adults than in children. Ibuprofen gels are widely available without a brand name, ie as the generic medicine. Other brands of ibuprofen that are applied to the skin include: Radian B muscle lotion contains menthol, camphor, ammonium salicylate and a mixture of methyl and ethyl esters of salicylic acid. The lotion works by reducing inflammation and by causing counter-irritation in the area where it is applied, which helps to soothe pain in the underlying tissues.

Radian B muscle rub - NetDoctor Radian B muscle rub - NetDoctor

Moderate] Nonsteroidal anti-inflammatory drugs (NSAIDs), including topicals, can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. Ibuprofen is absorbed into the bloodstream less when you apply it to the skin than when you take it by mouth, which means gels and sprays are less likely to cause side effects than products you take by mouth. However, absorption can still occur, particularly if you use large amounts on large areas of skin. How do I use Radian B ibuprofen gel? Ingestion of the product or excessive use may also lead to camphor poisoning, the symptoms of which include nausea, vomiting, epigastric pain, headache, dizziness, oropharyngeal burning, delirium, muscle twitching, epileptiform convulsions, CNS depression and coma. Breathing is difficult and the breath has a characteristic odour; anuria may occur. Death from respiratory failure or status epilepticus may occur; fatalities in children have been recorded from 1 g. Supportive care, including anticonvulsant therapy, is the mainstay of treatment of camphor intoxication. Gastric lavage may be considered if the patient presents within 1 hour of ingestion; any convulsions must be controlled first. Activated charcoal may be given orally.It is very well absorbed orally and the peak serum concentration can be attained in 1 to 2 hours after extravascular administration. When ibuprofen is administered immediately after a meal there is a slight reduction in the absorption rate but there is no change in the extent of the absorption. The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining. Avoid excessive sunlight exposure on the treated area as this may possibly lead to photosensitisation. For arthritic pain: The dosage range is from 0.9 to 2.4 g per day. The usual dose is 400 mg, 3-4 times per day, preferably after food. The dose may be raised to a maximum of 2.4 g daily depending on the severity of symptom at the time of initiating drug therapy or as patients fail to respond. After a satisfactory response has been achieved the patients dose should be reviewed and adjusted as required and tapered gradually.