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Mikosinski J, Di Landro A, Luczak-Szymerska K, et al. Efficacy and Safety of a Hyaluronic Acid-Containing Gauze Pad in the Treatment of Chronic Venous or Mixed-Origin Leg Ulcers: A Prospective, Multicenter, Randomized Controlled Trial. Wounds 2021;33(6):147-157. View abstract. You may have heard a lot in recent years about hyaluronic acid (HA), the wonder ingredient that has found its way into seemingly everything from face creams and foundations to shampoos and eyelash treatments. A brilliant hydrator, hyaluronic acid helps to plump up and retain moisture in the skin, smoothing away fine lines and wrinkles and giving skin a younger, fresher feel. Goa KL, Benfield P. Hyaluronic acid. A review of its pharmacology and use as a surgical aid in ophthalmology, and its therapeutic potential in joint disease and wound healing. Drugs 1994;47:536-66. View abstract.
Alcohol can be added to skincare to preserve or stabilize the formula. Greenfield recommends avoiding it as much as you can, explaining that formulas with alcohol “can end up drying out your skin rather than hydrating it.” We love the Paula's Choice Hyaluronic Acid Booster with Ceramides, which is not only alcohol-free, but contains a blend ceramides to enhance the formula’s soothing nature. Additional Ingredients Liu YR, Liu B, Yang BP, Lan Y, Chi YG. Efficacy of hyaluronic acid on the prevention of intrauterine adhesion and the improvement of fertility: a meta-analysis of randomized trials. Complement Ther Clin Pract 2022;47:101575. View abstract. So we all know hyaluronic acid to be the MVP of skincare—or, at least, that’s what you’ve read/heard/seen in every single article, commercial, and product description for the past year, right? (We get it, hyaluronic acid—YOU’RE POPULAR.) And although, yes, this little ingredient is usually the key to plump, glowing skin, it still needs to be used correctly or it could make your face sincerely unhappy. So if you have officially reached peak levels of confusion about WTF hyaluronic acid even is and how to use it, please allow myself and the experts to explain everything you need to know about hyaluronic acid for skin and the correct way to use it in your skincare routine. Meet the experts:Abdulkareem AA, Al Marah ZA, Abdulbaqi HR, Alshaeli AJ, Milward MR. A randomized double-blind clinical trial to evaluate the efficacy of chlorhexidine, antioxidant, and hyaluronic acid mouthwashes in the management of biofilm-induced gingivitis. Int J Dent Hyg. 2020;18(3):268-277. View abstract. Dougados M. Sodium hyaluronate therapy in osteoarthritis: arguments for a potential beneficial structural effect. Semin Arthritis Rheum 2000;30(2 Suppl 1):19-25. View abstract. Absorption: After applying each product, we took note of how long it took to absorb into our skin and whether it left behind any greasy residue. We also noted whether or not we could feel the product on our skin once it was fully absorbed. If we applied any skin products immediately before or after use, we took note of any interactions that occurred. John HE, Price RD. Perspectives in the selection of hyaluronic acid fillers for facial wrinkles and aging skin. Patient Prefer Adherence. 2009;3:225-230. doi:10.2147/ppa.s3183
Torretta S, Marchisio P, Rinaldi V, et al. Topical administration of hyaluronic acid in children with recurrent or chronic middle ear inflammations. Int J Immunopathol Pharmacol. 2016;29(3):438-42. Skinceuticals is a well-respected brand in the skin care market, but it doesn’t come cheap. Is it worth the splurge? According to multiple dermatologists who independently recommended it and our editors who tested it for eight weeks, when it comes to the Skinceuticals Hyaluronic Acid Intensifier, the answer is yes.Nava Greenfield, MD, is a board-certified dermatologist at Schweiger Dermatology Group in Brooklyn, NY. Greenfield is a member of the American Academy of Dermatology, the Women’s Dermatologic Society, and the American Medical Association. We all know there is no single wonder product that can stop skin ageing (unless Jennifer Lopez is keeping a secret stash to herself), but hyaluronic acid has been proven to plump the skin, minimise fine lines and reduce signs of dryness and dehydration. No wonder it's one of the beauty world's best face serums...
Voigt J., Driver VR. Hyaluronic acid derivatives and their healing effect on burns, epithelial surgical wounds, and chronic wounds: a systematic review and meta-analysis of randomized controlled trials. Wound Repair Regen. 2012;20(3):317-31. View abstract. Although hyaluronic acid works for all skin types, board-certified dermatologist Dr. Nava Greenfield recommends considering your skin type to find the one that suits your needs best. For example, if you have oily skin, she explains, you’ll want to look for a water-based product. We recommend the La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum for this. If you have dry skin, she says, try an oil- or cream-based serum for optimal hydration. The Peter Thomas Roth Water Drench Hyaluronic Glow Serum is one of our favorites for very dry skin. Alcohol-Free Formulations It’s up to you if you use your HA serum as part of your morning or your night-time routine; if applying in the morning, give the product time to sink in before applying moisturiser and makeup, as serum formulations can be quite runny and may cause your makeup to slide off if not properly absorbed.From the drugstore aisle, we’re loving Cerave’s Hyaluronic Acid Serum. It contains pure hyaluronic acid, plus vitamin B5 and three essential ceramides that work in tandem to hydrate, repair the skin’s barrier, and soften the entire face. While testing, we appreciated how promptly the formula absorbed into the skin (it took around 60 seconds) and it provided instant hydration. We found it to be very soothing and refreshing, plus we loved the fact that it didn’t sit atop the skin but rather seeped deep into our pores. Over the course of the testing period, our skin felt more hydrated overall (a huge win), with a huge difference in the softness of the previously dull and dry areas on our faces. Our T-zones never felt too oily, rather the serum provided a supple, glossy feel that proved to be a great base for both skincare and makeup. The only thing we wish we could change is that the bottle is a bit small; a larger bottle would last longer. But when you consider the price and accessibility (you can find it in any drugstore, no matter where you are), it can’t be beaten. Formulated with mature skin in mind, Dr. Dennis Gross’s Hyaluronic Marine Booster contains moisturizing watermelon extract and centella asiatica (aka cica) to smooth the appearance of fine lines. We like that this multifunctional serum can be applied all over the face or on dry patches as needed. Do note that the water-like consistency is runny, so consider using the dropper applicator to dispense the product directly on the skin to avoid waste. Ocak E, Mulazimoglu S, Kocaoz D, Mirici E, Dagli E, Acar A. Effect of adjunctive sodium hyaluronate versus surfactant nasal irrigation on mucociliary clearance in allergic rhinitis: a single-blind, randomised, controlled study. J Laryngol Otol 2021;135(6):529-532. View abstract. The serum contains fragrance, and although we found the scent calming and not at all overpowering, it could be irritating to very sensitive skin. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.
Farmacy Filling Good Hyaluronic Acid Serum: A clean option, we like the gentle ingredients in this formula for those with sensitive skin or anyone who actively avoids fragrance, parabens, and the like. We wanted to love it as much as the ingredients list, but at the end of the eight-week testing period, we couldn’t tell much of a difference. Compared to others we tested, this one fell short, though it feels and smells nice. If you have any questions or concerns, please don't hesitate to reach out to our friendly customer service team. GUARANTEED Calonge M, Sahyoun M, Baillif S, et al. Sodium hyaluronate 0.30% ocular gel versus sodium hyaluronate 0.18% eye drop in the treatment of moderate to severe dry eye disease. Eur J Ophthalmol 2023;33(1):188-95. View abstract. Lupo, M. P., Smith, S. R., Thomas, J. A., Murphy, D. K., and Beddingfield, F. C., III. Effectiveness of Juvederm Ultra Plus dermal filler in the treatment of severe nasolabial folds. Plast.Reconstr.Surg. 2008;121(1):289-297. View abstract.Hyaluronic acid has become something of a beauty buzzword and not without good reason. It may sound like something you'd use with a Bunsen Burner in a GCSE science class, but it's actually the one ingredient you need to add to your skincare routine, ASAP. If you put hyaluronic acid on top of a sunscreen or a moisturizer, it’s not going to work,” Dr. Talakoub says. “It’s got to sit on that top layer of your skin to hold the moisture in so it doesn’t evaporate from your skin barrier.” This serum is an amazing choice for anyone dealing with hormonal changes such as pregnancy or postpartum. Uthman, I., Raynauld, J. P., and Haraoui, B. Intra-articular therapy in osteoarthritis. Postgrad.Med J 2003;79(934):449-453. View abstract. Delia P, Sansotta G, Pontoriero A, et al. Clinical Evaluation of Low-Molecular-Weight Hyaluronic Acid-Based Treatment on Onset of Acute Side Effects in Women Receiving Adjuvant Radiotherapy after Cervical Surgery: A Randomized Clinical Trial. Oncol Res Treat. 2019;42(4):217-223. View abstract.
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