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Pet Wellbeing Milk Thistle for Cats - Supports Liver Health, Protects Liver - Glycerin-Based Natural Herbal Supplement - 2 oz (59 ml)

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Milk thistle contains a strong anti-oxidant ingredient, silymarin, so it also helps cells fight against free radicals. Diabetes medications. Milk thistle might lower blood sugar in people who have type 2 diabetes. Closely monitor your blood sugar levels, and talk to your doctor before taking milk thistle supplements if you take diabetes medications. Habib, R. (n.d.) Milk thistle for your dog. Dogs Naturally Magazine. Retrieved 2/7/2020 from https://www.dogsnaturallymagazine.com/milk-thistle-for-your-dog/ Milk Thistle for cats with liver disease is glycerin-based and safe for long-term use. This potent herbal formula provides excellent proactive support and can be taken in conjunction with conventional treatment. Liver: Milk thistle acts as a liver protectant. It is especially beneficial in animals recovering from parvovirus, inoculations, frequent antibiotic use, exposure to contaminants such as aflatoxin in contaminated commercial food ( 3), jaundice ( 4), toxic byproducts of pharmaceutical drugs and many newer liver diseases coming to scientific light ( 5). It also helps with hepatic lipidosis (replacement of healthy liver cells with fat) and chronic hepatitis.

Milk Thistle’s beneficial effects are largely down to the active compound found in the seeds and fruit called silymarin. There are however other compounds present in the fruit that also have a potential role to play in supporting the liver, and wider body. Healthy oils such as linoleic acid, flavenoids, and vitamin E are all known for their antioxidant (to neutralise free radicals) and immune supportive action and all are present in the Milk Thistle fruit.

Nutramed is a particularly useful supplement for older dogs who need multiple health support. Increasingly, nutraceuticals are playing a beneficial multimodal role in aiding recovery, naturally. If you are looking for a natural liver supplement for dogs or cats, then Nutramed is recommended by vets throughout the UK as a triple strength formula and a natural alternative for animal healthcare. Denamarin is a liver health supplement that contains the two main ingredients s-adenosylmethionine (SAMe, pronounced “sam-ee”) and silybin. Recent studies have shown to moderate the pro-inflammatory cascade as well as having a beneficial effect on aiding healthy liver function. Milk Thistle is a natural supplement, well-known for helping with liver support in cats, dogs and humans alike. The ingredients in Denamarin can help to protect liver cells from toxins and inflammatory damage through the actions of silybin, as well as improve liver function through SAMe’s involvement with major metabolic processes of the liver.

Milk Thistle is a safe herb that is well tolerated by your pet. It is herb that is recommend and used by holistic practitioners An overdose of milk thistle can upset the stomach, cause diarrhea and gas. Discontinue the treatment if you notice any of these symptoms. These symptoms will subside once the dose is adjusted. Milk thistle has proven to be useful in acetaminophen toxicity in cats whose well-meaning owners have dosed them with the drug for their aches and pains ( 8). Singh, S., Shukla, S.K., Bhatt, P and Singh, A. K. (2019). Clinico therapeutic studies on ascites in canines. International Journal of Current Microbiology and Applied Sciences, 8(9): 1120-1137. Retrieved from https://doi.org/10.20546/ijcmas.2019.809.129 This supplement by NHV Natural Pet Products uses 100% natural milk thistle to support dogs through liver and kidney conditions in addition to conventional treatment by their veterinarian. Liver Support Benefits

Milk Thistle aids in supporting the liver by decreasing aminotransferase activity (important in the synthesis of amino acids which form proteins that are an important indicator of liver damage). In our experience, using NHV Milk Thistle Extract has greatly reduced elevated blood liver enzymes and helped to treat liver disease. What Are Some Other Beneficial Uses of Milk Thistle For Cats and Dogs? We believe Milk Thistle would also be beneficial to your little one as traditional medications can be tough on the liver and kidneys. Milk Thistle can help to improve liver and kidney function and can encourage liver regeneration. Treatment with milk thistle may also be indicated for dogs on steroids, heartworm prevention, or anti-inflammatory medication as well as an adjunct to chemotherapy ( 10).

Allergies: Milk thistle helps alleviate epidermal and other signs of allergy due to high histamine levels ( 1).Help maintain good liver function in your pet with our high-grade Milk Thistle Tablets for dogs and cats. The liver is the ultimate multi-tasker, involved in almost all body processes, including the production of essential proteins, immunity and nutrient storage. It is also a powerhouse when it comes to toxins, removing and neutralising harmful substances from the circulation. Our supplement naturally supports the liver, using pure milk thistle from whole fruit extract. It is high in silymarin, but also benefits from the other active compounds found in milk thistle fruits. How does Milk Thistle work? We thought you might want to take a look at this blog we have that has lots of good tips on how to naturally manage diabetes in pets: https://nhvpethealth.com/blog/vet-tech-rounds-how-to-best-help-a-diabetic-cat/ Avizeh, R, Najafzadeh, H., Razij-jalali, M., and Shirali, S. (2010) Evaluation of prophylactic and therapeutic effects of silymarin and N-acetylcysteine in acetaminophen-induced hepatotoxicity in cats. Journal of Veterinary Pharmacology and Therapeutics, 33(1). Abstract retrieved from https://doi.org/10.1111/j.1365-2885.2009.01100.x In veterinary medicine, an interesting study has recently been performed on 8 dogs presenting hepatopathy, given a phytocomplex of Silybum marianum pure extract. After two months of administration, a reduction of plasma alanine aminotransferase (ALT)/glutamate-pyruvate transaminase (GPT) activity was obtained; remarkably, the study also included other groups of dogs, given other nutraceuticals, and the activity of this enzyme only decreased in the hepatopathy group. Furthermore, in these dogs, the significant increase of paraoxonase and the up regulation of mitochondrial SOD2 suggest an antioxidant activity for this phytocomplex in dogs. Unfortunately, as also stated by the authors, although results are interesting and suggest a positive effect of Silybum marianum in hepatopathies, the inclusion of only eight dogs in the study limits is its clinical relevance [ 12]. Remarkable are also the results obtained by Skorupski et al. that investigated the effect of the combination S-adenosylmethionine and silybin-phosphatidylcholine complex to prevent hepatopathy in dogs receiving lomustine, as affected by different kinds of neoplasm. Additionally, supplemented dogs showed a lower increase of ALT/GPT, alkaline phosphatase, bilirubin, and aspartate aminotransferase than dogs treated with lomustine alone [ 13]. Other less recent experimental studies on silymarin and silibinin have been performed on dogs given Amanita phalloides/phalloidin [ 19]. In one case, the effect of intravenous silymarin (and other molecules) was tested in experimentally poisoned dogs, and this molecule showed to prevent/reduce the increase of alkaline phosphatase (AP), GPT, and aspartate aminotransferase (AST)/glutamic-oxalacetic transaminase (GOT), reduce the severity of clinical signs, and also exerted some positive effects on coagulation [ 18]. Finally, intravenous administration of silibinin in beagles receiving a lyophilysate of Amanita Phalloides, containing α-, β-, and γ-amanitin and phallotoxins likewise resulted in a reduced hepatoxicity (measured by ALT/GPT, AST/GOT, AP, bilirubin, and prothrombin time), reduced liver damage (histological assessment), and absence of mortality [ 17]. Very few studies have been performed on the topic of the present paper on cats. One of these reports the efficacy of silymarin in healthy cats given acetaminophen; in these animals, levels of ALT/GPT, AST/GOT, alkaline phosphatase, lactate dehydrogenase, methemoglobin, and bilirubin did not increase as it happened in cats given acetaminophen alone [ 14]. Numerous complementary feeds to support liver function are commercially available for small animals. Aiming to furnish a scientific support for clinicians/nutritionists that necessitate a complementary feed to support liver function in dogs and cats, with the present paper, we analyzed scientific evidences supporting the use, for this purpose, of ingredients/additives such as artichoke ( Cynara scolymus), curcumin, dandelion ( Taraxacum officinale), milk thistle ( Silybum marianum), phosphatidylcholine, and S-adenosylmethionine. Although sustained by significant results, our review found only few scientific papers, and albeit we believe that they represent a significant aid in handling hepatopathies, in the authors’ opinion, this topic probably deserves, and would benefit of, further studies. 1. Introduction

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