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In multiple logistic regression analysis adjusted for age, the odds ratio (OR) of incident diabetes for vegans was 0.228 (95% CI 0.140, 0.372), lacto ovo vegetarians, 0.461 (95% CI, 0.373, 0.569), pesco vegetarians, 0.597 (95% CI 0.433, 0.823), and semi-vegetarians, 0.380 (95% CI 0.236, 0.613) compared to the non-vegetarian reference group. With adjustment for age and BMI, these point estimates were somewhat weakened but remained statistically significant with the exception of the pesco vegetarian group. For vegans the OR was 0.383 (95% CI 0.233, 0.629), for lacto ovo vegetarians, 0.635 (95% CI, 0.511, 0.789), for pesco vegetarians 0.791 (0.572, 1.095) and for semi-vegetarians 0.447 (95% CI 0.277, 0.722). Adjustment for lifestyle factors in addition had very minor effects on the estimates compared to the age and BMI adjusted results (data not shown). Appleby PN, Davey GK, Key TJ. Hypertension and blood pressure among meat eaters, fish eaters, vegetarians and vegans in EPIC-Oxford. Public Health Nutr. 2002;5:645–54. Tonstad S, Stewart K, Oda K, Batech M, Herring RP, Fraser GE. Vegetarian diets and incidence of diabetes in the Adventist Health Study-2. Nutr Metab Cardiovasc Dis [Internet]. 2013 Apr [cited 2017 Sep 11];23(4):292–9. Available at: http://www.ncbi.nlm.nih.gov/pubmed/21983060 [11.06.2018] Conclusions These non-randomized data across U.S. clinical practices show high and stable vaccine effectiveness of Ad26.COV2.S over time before the Delta variant emerged to when the Delta variant was dominant. Competing Interest Statement

Pineles SL, Kraker RT, Vanderveen DK, et al. Atropine for the prevention of myopia progression in children: a report by the American Academy of Ophthalmology. Ophthalmology. 2017;124(12):1857–1866. Bellavia A, Stilling F, Wolk A. High red meat intake and all-cause cardiovascular and cancer mortality: is the risk modified by fruit and vegetable intake? Am J Clin Nutr. 2016;104:1137–43.Furthermore, a plant-based diet reduces the risks of foodborne illnesses from salmonella and other bacteria, as well as exposure to environmental toxins. Important nutrients in a vegan diet Pulses such as lentils, peas, beans, soybeans, and lupins are a key so urce of protein. [4] Daniel, P., Harvard University (2017): How much protein do you need every day? Available at: https://www.health.harvard.edu/blog/how-much-protein-do-you-need-every-day-2015 [11.06.2018]

Mcbrien NA, Moghaddam HO, Reeder AP. Atropine reduces experimental myopia and eye enlargement via a nonaccommodative mechanism. Invest Ophthalmol Vis Sci. 1993;34(1):205–215. Guggenheim JA, Northstone K, Mcmahon G, et al. Time outdoors and physical activity as predictors of incident myopia in childhood: a prospective cohort study. Invest Ophthalmol Vis Sci. 2012;53(6):2856–2865. Tonstad S, Butler T, Yan R, Fraser GE. Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care [Internet]. American Diabetes Association; 2009 May [cited 2017 Sep 11];32(5):791–6. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19351712 [11.06.2018] Scarborough P, Appleby PN, Mizdrak A, et al. Dietary greenhouse gas emissions of meat-eaters, fish-eaters, vegetarians and vegans in the UK. Clim Change. 2014;125:179–92.Throughout history, plant-based diets have always played a role, whether for religious, political, or social reasons. The concept of vegetarianism first gained cultural prominence in the 8th century BC, originating from a religious predecessor of hinduism in Indian cultures. But even in Europe, during the 6th century BC, certain schools of Greek philosophy rejected the consumption of meat for ethical and, later on, for economic, ecological, or health reasons. [1] Leitzmann, C. & M. Keller (2010): Vegetarische Ernährung. Stuttgart: Verlag Eugen Ulmer, 2. Ed., p. 37-38 [2] The Vegan Society: History. Available at: https://www.vegansociety.com/about-us/history [12.06.2018]. What to eat on a vegan diet of Ophthalmology, Southern California Medical Group, Los Angeles, CA, USA; 2Department of Ophthalmology, Southern California Permanente Medical Group, Baldwin Park, CA, USA; 3Eye Monitoring Center, Kaiser Permanente Southern California, Baldwin Park, CA, USA; 4Department of Research and Evaluation, Southern California Permanente Medical Group, Pasadena, CA, USA Varma R, Tarczy-Hornoch K, Jiang X. Visual impairment in preschool children in the United States: demographic and geographic variations from 2015 to 2060. JAMA Ophthalmol. 2017;135(6):610–616.

Odds ratios with 95% confidence intervals for incident diabetes by dietary group adjusted for age, BMI, ethnicity, gender, educational level, income, TV watching, sleep, alcohol, physical activity and cigarette smoking. Harvard T. H. Chan (2018): Whole Grains. Available at: https://www.hsph.harvard.edu/nutritionsource/whole-grains/ [11.06.2018]

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Wu LJ, You QS, Duan JL, et al. Prevalence and associated factors of myopia in high-school students in Beijing. PLoS One. 2015;10(3):e0120764.