The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

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The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

The Epigenetics Revolution: How Modern Biology is Rewriting Our Understanding of Genetics, Disease and Inheritance

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Like many other biologists writing for a wider audience, Dawkins prefers the metaphor of genes as ingredients in a recipe. Often such children who suffered from abuse or neglect in their early years have substantially higher risk as adults of mental health problems than the general population. The grounds for excitement stem from the fact that this old and frequently sterile dichotomy is now being fleshed out with real knowledge of how genes are controlled and how they respond to life situations. The book is organized around themes and levels of interaction/processes in the biological hierarchy in which epigenetics acts. She reveres the philosophies of science, in particular the principle of hypothesis and test, the crucial importance of a well-chosen experimental system, and the power of incisive thought.

The famous double helix of DNA was one of the most impressive scientific images of the second half of the twentieth century. Carey] provides an excellent and largely accurate account of a fascinating and fast-moving area of modern biology. Approximately 98 percent of the DNA in the human genome is non-coding (exons), which means that it does not encode a protein, however this does not mean that it has no function. That something else must be going on in addition to the instructions contained in the genetic code is clear from the following simple fact. But I want to reassure the reader because in the overwhelming number of cases, Darwinian evolution prevails.

And this is exactly what has been achieved by using complicated networks of ncRNAs molecules to influence how, when and to what degree specific proteins are expressed.

All the (somatic) cells in our body have exactly the same set of genes, but not all cells are the same. Just over a decade since Matt Ridley's seminal Genome, Nessa Carey presents a hugely compelling explanation of the very latest from the frontline of modern biology.That said, there was much I did enjoy, especially her ability to switch between the nitty gritty account of lab work and a more abstract analysis of the scientific method. It’s the fastest moving field in modern biology, yet very little has been written on this for a general readership. We have similarly come to the realization that the complexity of living organisms scales much better with the percentage that does not code for proteins than it does with the number of base pairs coding for proteins. Something suggesting Lamarckian inheritance and this is indeed what happened and has a name 'transgenerational inheritance'.

An exhilarating exploration of an exciting new field, and a good gift for a bright biology student looking for a career choice. Genes don't just issue instructions: they respond to messages coming from other genes, from hormones and from nutritional cues and learning. I would recommend The Epigenetics Revolution highly to anyone seeking an introduction to epigenetics. For nearly ten years she has worked in the biotech industry, trying to take basic science discoveries and turn them into new treatments for human diseases.

Evolution seems to have solved the problem of creating more complex and sophisticated organisms by altering the regulation of the organisms than altering the proteins themselves. The analogy that DNA is a script to be interpreted is a particularly articulate explanation for novice readers.



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