Peak blood levels of free acetaminophen are not reached until 3 hours after rectal administration of the suppository form of acetaminophen and the peak blood concentration is approximately 50% of the observed concentration after the ingestion of an equivalent oral dose (10-20 mcg/mL). In 2-year feeding studies, F344/N rats and B6C3F1 mice consumed a diet containing acetaminophen up to 6,000 ppm. The binding of acetaminophen to plasma proteins is low (ranging from 10% to 25%), when given at therapeutic doses. Lemsip max cold and flu capsules contain caffeine, so you should avoid drinking lots of caffeine-containing drinks, such as tea, coffee, cola, while you're taking this medicine. While prospective clinical studies examining the results of nursing with acetaminophen use have not been conducted, acetaminophen is found secreted in human milk at low concentrations after oral administration.

The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so Lemsip max flu lemon might take longer to work if you are using one of these medicines to treat your diabetes. If you take Lemsip cough max for mucus cough and cold in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. Relieving the symptoms of colds and flu, such as headache, sore throat, aches and pains, fever and blocked nose or sinuses for adults aged 16 years and over. As opposed to the salicylate drug class, acetaminophen does not disrupt tubular secretion of uric acid and does not affect acid-base balance if taken at the recommended doses.

Consult a GP if your catarrh persists, isn’t improving with care, or you’re experiencing a lot of discomfort. However, do not take them with co-codamol, co-dydramol or Tramacet because these contain paracetamol.

The maximum dose may vary from 3,000 mg to 4,000 mg, but do not take more than 4,000 mg in a 24-hour period.MAOIs include the antidepressants phenelzine, tranylcypromine, isocarboxazid and moclobemide, and the anti-Parkinson's medicines selegiline, safinamide and rasagiline. Lemsip cough max for mucus cough and cold capsules: Each capsule contains 500mg paracetamol, 100mg guaifenesin and 6.

Guaifenesin has been linked with an increased risk of neural tube defects in a small number of women with febrile illness in the first trimester of pregnancy.

But it's also important to never stop taking a medicine that's been prescribed to keep you healthy without first checking with your doctor.

Though acetylsalicylic acid (aspirin) is an irreversible inhibitor of COX and directly blocks the active site of this enzyme, studies have shown that acetaminophen (paracetamol) blocks COX indirectly. For more information about the possible side effects of Lemsip max flu lemon, read the information provided with the medicine or talk to your doctor or pharmacist. Their original and best-known product is a lemon-flavoured hot drink containing 650mg of paracetamol (an analgesic), and 10mg phenylephrine hydrochloride (a decongestant) to help to relieve headache, fever, blocked nose, body aches and pains, and a sore throat.

Lemsip is an analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.